MSE Natural Defense is a natural probiotic for pets with allergies, for those that experience stress on a daily basis, or for maximum control of litter box odor. It can help control loose stools and diarrhea, which are often a symptom of Exocrine pancreatic insufficiency (EPI) and Irritable bowel syndrome (IBS). MSE Natural Defense has also been shown to reduce the symptoms of allergy in most dogs. The body reacts to allergens (both food and environmental) as if they were pathogens. Allergies are actually an immune response that results in chronic scratching and biting. Constant irritation and scratching is stressful, and stress reduces the ability of the body to fight infection. This means an allergic pet is trapped in a vicious cycle that leaves them vulnerable to infection. Break the cycle by feeding MSE Natural Defense every day. MSE Natural Defense contains a substance that has been shown to block the immunoglobulin that triggers allergy symptoms. Kidney failure in cats and dogs - Conventional treatment for kidney failure is to reduce protein in the diet. However, intact protein is too large to escape through the gut wall, it must be disassembled by proteases first. The only part of the disassembled protein that can cause damage is the amine group (NH3). This is safely bound into the urease molecule and transported to the kidneys for disposal as ammonia in the urine. Nitrogen and ammonia are both toxic and must be diluted with water to reduce kidney damage. Prevents and minimizes kidney damage by trapping urease in the gut and excreting via the feces. Ammonia reduction also means less litter-box odor. Cat urine has a higher concentration of ammonia than that of dogs, and cats also have a significantly higher incidence of kidney failure (10% in dogs v. 25% in cats). MSE Natural Defense can reduce both litter-box odor and the incidence and extent of kidney failure. Ingredients: A proprietary blend of Lactobacillus acidophilus, Lactobacillus casei, Streptococcus faecium, Bifidobacterium longum, and Saccharomyces cerevisiae, plus pectin.